SUPREME-SECURE is a Unitaid-funded program working to strengthen sustainable access to quality-assured diagnostics and treatments for preeclampsia, eclampsia, and maternal anemia in sub-Saharan Africa. CHAI is leading this initiative in partnership with Concept Foundation, Aurum Institute, Burnet Institute, and WACI Health.
As part of the programme’s work to strengthen access to quality-assured, affordable diagnostics, Concept Foundation is now accepting two Requests for Proposals (RFPs) from manufacturers of point-of-care preeclampsia biomarker assays. Through these RFPs, SUPREME-SECURE aims to identify promising technologies for independent evaluation, regulatory advancement, and introduction in low- and middle-income countries.
RFP 1 (PE003): Near Point-of-Care sFlt-1 and/or PlGF Assays
- Product category: quantitative immunoassay for angiogenic biomarkers associated with placental dysfunction, for use as an aid in diagnosing preeclampsia.
- Intended use: aid in diagnosis and short-term prediction (rule in/out) of preeclampsia in pregnant women with suspected disease, used alongside standard-of-care assessment.
- Target population: pregnant women from 20+0 weeks gestational age with suspected preeclampsia.
RFP 2 (PE004): Minimally Invasive Biomarkers
- Product category: point-of-care assay detecting biomarkers associated with preeclampsia, using minimally invasive specimens (capillary blood, urine, or saliva), for screening and/or diagnosis.
- Intended use: early risk screening and/or aid in diagnosis and short-term prediction (rule in/rule out) of preeclampsia, used alongside standard-of-care assessment.
- Target population: pregnant women under 20 weeks gestational age (early risk screening) and/or from 20+0 weeks with suspected preeclampsia (diagnosis and short-term prediction).
Target countries for both RFPs include Ghana, Kenya, Malawi, Senegal, Tanzania, and South Africa, with potential for broader LMIC reach.
An information session covering both RFPs will be held on Friday, July 17, 2026 — register here.
Proposal submission deadline (both RFPs): Friday, August 7, 2026
Questions? Contact Concept Foundation at rfp_dx@conceptfoundation.org
