Hepatitis

Hepatitis
The Issue
Viral hepatitis— hepatitis C (HCV) and hepatitis B (HBV) — affects more than 320 million people worldwide, with 90 percent of infections concentrated in low- and middle-income countries. The disease leads to significant liver damage, liver cancer, and liver failure. Although HCV is curable in more than 95 percent of patients with direct-acting antivirals (DAAs), only seven percent of those infected receive treatment. Many factors contribute to this gap, including limited awareness of HCV, lack of public screening and treatment programs, and historically high costs of care. Similarly, HBV is vaccine-preventable, yet impacts more than 250 million people worldwide. In low- and middle-income countries, only a fraction of those in need receive the vaccine as infants or treatment as adults.
CHAI's Approach
CHAI is committed to eliminating HCV. We have developed a strategy that aims to cure over 16 million people in 34 countries over the next ten years. Since 2015, CHAI has helped governments in six countries initiate public HCV programs to simplify patient diagnosis and monitoring and lower the costs of medications to save millions of lives. We have helped, through market shaping and price negotiations, lower the cost of treatment by 81 to 97 percent (depending on the country), from an average of US$2,618 to as low as US$60 per cure. Since the program’s inception, over 100,000 patients have been initiated on treatment in the countries where we work. This initial push has demonstrated effective models that can serve as guides to the countries that follow.
To help prevent new HBV infections, we are partnering with Gavi, The Vaccine Alliance, as well as governments, to organize programs to administer the HBV birth dose more effectively. We are leveraging existing relationships with national HIV, HCV and maternal health/antenatal care programs to support the integration of HBV diagnosis and treatment within already established systems.
Results
US$60
HCV cost-per-cure, reduced from US$2,618
97%
price reduction in cost-per-patient treated for HCV
+100K
patients treated for HCV through CHAI support
Our Work
Text on graphic reads: AIDS 2022 29 July - 2 August Montreal and Virtual 2.

August 4, 2022

Four takeaways from the AIDS 2022 Conference

Global AIDS fight ‘in danger’ but there is still time to get back on track, participants hear at AIDS 2022 conference. A few short weeks ago, CHAI marked the start of our 20th anniversary. We remembered the 2002 AIDS conference in Barcelona, which helped launch our organization, and the barriers to treatment people living with HIV faced...

Read More
A nurse squeezes a few drops of blood to screen for hepatitis infection at Rwamagana, Rwanda

July 25, 2022

Hepatitis programs should invest in hepatitis services to procure diagnostics and drugs at affordable prices

CHAI’s recently released Hepatitis C Market Memo is an update to the previous editions of Hepatitis market reports. It provides critical insights into the market and helps the public and private sectors develop better strategies to provide products and services to those who need them. Every 30 seconds, someone loses their life to a hepatitis-related...

Read More
Report cover of Hepatitis C Market Memo July 2022

July 25, 2022

CHAI releases the 2022 Hepatitis C Market Memo

CHAI is excited to publish the 2022 Hepatitis C Market Memo, covering the latest trends in the hepatitis C diagnostics and treatment markets. The memo provides updates on key innovations, volume, and pricing trends for hepatitis programs seeking to eliminate the disease.

Read More
Report cover with CHAI logo at top left with title below that reads HCV Market Intelligence Report 2021 and Preliminary HPV Market Insights. Background is blue and circles with various images of HCV diagnostics inside, tinted yellow, run diagonally across the page.

August 25, 2021

CHAI releases second edition of Hepatitis C Market Report

The report provides market intelligence on hepatitis C diagnostics and drugs in low- and middle-income countries and covers preliminary insights into the hepatitis B market.

Read More
Text on graphic reads: AIDS 2022 29 July - 2 August Montreal and Virtual 2.

August 4, 2022

Four takeaways from the AIDS 2022 Conference

Global AIDS fight ‘in danger’ but there is still time to get back on track, participants hear at AIDS 2022 conference. A few short weeks ago, CHAI marked the start of our 20th anniversary. We remembered the 2002 AIDS conference in Barcelona, which helped launch our organization, and the barriers to treatment people living with HIV faced...

Read More
A nurse squeezes a few drops of blood to screen for hepatitis infection at Rwamagana, Rwanda

July 25, 2022

Hepatitis programs should invest in hepatitis services to procure diagnostics and drugs at affordable prices

CHAI’s recently released Hepatitis C Market Memo is an update to the previous editions of Hepatitis market reports. It provides critical insights into the market and helps the public and private sectors develop better strategies to provide products and services to those who need them. Every 30 seconds, someone loses their life to a hepatitis-related...

Read More
Report cover of Hepatitis C Market Memo July 2022

July 25, 2022

CHAI releases the 2022 Hepatitis C Market Memo

CHAI is excited to publish the 2022 Hepatitis C Market Memo, covering the latest trends in the hepatitis C diagnostics and treatment markets. The memo provides updates on key innovations, volume, and pricing trends for hepatitis programs seeking to eliminate the disease.

Read More
Report cover with CHAI logo at top left with title below that reads HCV Market Intelligence Report 2021 and Preliminary HPV Market Insights. Background is blue and circles with various images of HCV diagnostics inside, tinted yellow, run diagonally across the page.

August 25, 2021

CHAI releases second edition of Hepatitis C Market Report

The report provides market intelligence on hepatitis C diagnostics and drugs in low- and middle-income countries and covers preliminary insights into the hepatitis B market.

Read More

Join Our Team

CHAI is looking for dynamic and self-motivated individuals who are committed to strengthening health systems around the world and expanding access to care and treatment of HIV/AIDS, malaria, and other illnesses.

View All CHAI Positions View Program Positions

Join Our Team

CHAI is looking for dynamic and self-motivated individuals who are committed to strengthening health systems around the world and expanding access to care and treatment of HIV/AIDS, malaria, and other illnesses.

View All CHAI Positions View Program Positions