CHAI’s work in Latin America and the Caribbean began in 2004, supporting governments in the Caribbean to expand access to HIV diagnostics and treatment—an effort that helped establish our long-standing partnerships in the region. Building on this foundation, we expanded our focus in 2014 to support national malaria elimination efforts in the Dominican Republic, Guatemala, Haiti, Honduras, and Panama.

Our malaria work takes a comprehensive, systems-strengthening approach: reinforcing community health worker (CHW) networks to improve case detection, diagnosis, and treatment in high-burden communities, while strengthening surveillance, case management, and vector control. We have supported the introduction of targeted interventions including indoor residual spraying, rapid diagnostic tests, and digital surveillance tools. A major milestone was the creation of the Regional Malaria Elimination Initiative (RMEI), a US$100 million blended financing mechanism bringing together endemic countries and global partners. Today, we are building on this progress by integrating CHWs into government-led primary care systems and strengthening the data, financing, and strategic planning needed to drive transmission to zero—particularly in indigenous and underserved communities.