Annual Report 2024

Zimbabwe health workers receive PPE from donors

Annual Report 2024

Putting our strategy to work in 2024

When we launched our 2024-2028 strategy, we set out to tackle persistent global health challenges through four strategic objectives: scaling proven solutions, accelerating innovation, extending the value of health spending, and strengthening health systems. As this report demonstrates, that strategy is delivering real results.

However, in the interim, the global health landscape has shifted dramatically. The next era of global health will look markedly different than the last—but we also have an unprecedented opportunity to make it better. The impact stories in this report prove that progress remains possible. When we combine proven interventions with innovative approaches, leverage every dollar for maximum impact, and build systems that can adapt—we can still achieve our vision: a world where everyone has the opportunity to live a healthy and fulfilling life.

CHAI’s impact

600%

increase in breast cancer treatment for Ethiopian women between 2019 and 2024

7.39M

girls vaccinated against HPV in conflict-affected areas of Nigeria

78%

increase in hormonal IUD use in seven African countries, preventing 271,000 unintended pregnancies

97%

of children with severe malnutrition in Lao PDR pilot province on treatment, up from 10% in 2023

365 to 2

HIV prevention simplified from 365 daily pills to twice-yearly injection, with CHAI scaling generic access

2,000+

ultraportable x-ray machines India’s national TB program is procuring to aid screening in remote communities

1.4M

Rwandan women covered for cervical, breast cancer care via health insurance

25 weeks

with zero malaria cases reported in Escuintla, Guatemala, in 2024, demonstrating near-elimination

49.6M

people screened for hepatitis B and C since 2016 in eight countries, with 13.2M screened in 2024 alone

Highlights

A woman with her four children sitting on a blue couch

Ethiopia achieves 600% increase in breast cancer treatment by decentralizing services

In Ethiopia, women with breast cancer have low survival rates due to late-stage diagnosis, limited access to treatment, and resource constraints. CHAI partnered with Ethiopia’s Ministry of Health to decentralize services and train health workers at all levels of care.

The results were dramatic: In 2024, 38,000 women received their first clinical breast exam. And 6,132 women were treated for breast cancer—a 600 percent increase from 2019. Breast cancer services expanded to 22 additional health facilities, a 12-fold increase, allowing 26,000 patients to receive cancer care. Building on this success, Ethiopia launched its first-ever National Breast Cancer Guidelines in 2024 to standardize care across the country, positioning Ethiopia as a leader in NCD care delivery in the region.

A woman with her four children sitting on a blue couch

CHAI Impact Spotlight

“In Laos, we solved a critical gender equity problem in malaria treatment. Previously, only men could receive radical cure treatment due to testing limitations. Working with the National Control Program since 2018, our team piloted new diagnostic tools and shifted national guidelines from qualitative to quantitative G6PD testing. The results were transformative: radical cure coverage for P. vivax patients jumped from just over 24 percent in 2019 to 93 percent in 2024, and now women can finally access the same life-saving treatment as men.”

Vilayphone Phongchantha

Senior Program Manager, Malaria, Dengue, and EOC, Lao PDR

A Cambodian elderly lady covers one eye with her hand as her eye sight is tested

100,000+ set to receive eyeglasses through innovative delivery models

Globally, one billion people need eyeglasses. In 2024, CHAI partnered with governments to expand access through cost-effective delivery models that promote first-time use and affordable, quality glasses.

The results: in Cambodia and Uganda, in-school screening campaigns led to almost 120,000 children and teachers getting screened, and those who needed them, receiving glasses. In South Africa, community campaigns led to 21,000 uninsured people receiving glasses. While in Nigeria, CHAI supported a Presidential initiative to provide five million reading glasses to people over 40. In the first month, 12,000 pairs were distributed—60 percent to first-time users. These examples demonstrate how targeted interventions can close critical gaps in access to vision care.

A Cambodian elderly lady covers one eye with her hand as her eye sight is tested

CHAI Impact Spotlight

“Nigeria’s shortage of mental health specialists meant adolescents living with or at-risk of HIV couldn’t access critical mental health services. Leading CHAI’s HIV-Mental health integration project since 2019, we adopted WHO’s mhGAP 3.0 guidelines, positioning Nigeria among the first countries globally to implement this framework. We trained over 130 healthcare workers directly, with hundreds more reached through cascade training. The impact: over 6,500 adolescents screened and 264 clients receiving psychosocial support, while our digital solutions—including USSD codes for university students—scaled access without scaling costs.”

Nere Otubu

Associate Director, HIV & TB – Access Program, Nigeria

Testing for COVID-19

AI technology brings expert TB diagnosis to remote communities in India

CHAI is introducing portable US$11 chest X-rays with AI-powered analysis to provide expert-level TB diagnosis in places without radiologists. In India, these machines address a clinical challenge: 43 percent of TB cases are asymptomatic, meaning traditional symptom-based screening misses nearly half of patients.

Through community-based screening in 11 states, CHAI-affiliate the William J. Clinton Foundation screened over 721,000 people in 2024, diagnosing nearly 6,000 cases—a third of which were asymptomatic and would have otherwise gone undetected.

This evidence drove India’s national TB program to procure over 2,000 ultraportable X-ray machines over the next two years, enabling millions more screenings annually and preventing thousands of deaths. The model shows how emerging technology can leapfrog traditional development pathways.

A woman with her four children sitting on a blue couch

CHAI Impact Spotlight

“Coming from a chemical engineering background, I joined CHAI Eswatini in 2023 to tackle critical health infrastructure challenges. My first project analyzed the medical oxygen supply ecosystem, and the data we gathered informed an oxygen sustainability plan and enabled construction of critical infrastructure. Moving to the health financing team, I used data-driven insights to improve central medical stores operations by increasing visibility into commodity availability and supplier performance. Now I’m developing renewable energy solutions for health facilities, working across three ministries to address rising electricity costs and direct resources toward facilities most affected by energy insecurity.”

Thandolwethu Hlatshwayo

Associate, Solar Electrification, Eswatini

Testing for COVID-19

Lao PDR pilot achieves 97% malnutrition treatment coverage, paving way for national scale-up

An estimated 10.7 percent of children under five in Lao PDR suffer from acute malnutrition. Critical gaps—including limited understanding of screening protocols, inadequate access to supplies, and weak record keeping—persist.

In Attapeu Province, CHAI introduced a Service Readiness-Service Delivery model across all hospitals and health centers. Throughout 2024, CHAI conducted monthly data reviews to assess equipment availability and routinely monitored service delivery, giving the government visibility into gaps and enabling targeted interventions.

The results: within one year, the percentage of children receiving ready-to-use therapeutic food treatment rose from 10 percent to 97 percent. This proven approach now provides a replicable blueprint for national scale-up, demonstrating how systematic data use can rapidly improve health outcomes across the country.

A woman with her four children sitting on a blue couch

Thank you to our many partners and donors for their tireless commitment to saving lives and ensuring that all people, no matter where they live, have access to quality, affordable health services. View the full list here.

Download the
2024 Annual Report

This year’s report checks in with our 2024-2028 strategy and our work to tackle persistent global health challenges even as the global health landscape has shifted.
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